The AlphaLISA® SureFire® Ultra™ Human and Mouse Total SMAD4 assay is a sandwich immunoassay for quantitative detection of total SMAD4 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
SMAD family member 4 (SMAD4), also known as mothers against decapentaplegic homolog 4, or DPC4 (deleted in pancreatic cancer-4), belongs to the SMAD family of transcription factor proteins, which act as mediators of TGF-β signal transduction. In conjunction with SMAD 2 and SMAD 3, the SMAD2/3/4 complex forms and acts as a transcription factor that promotes the expression of a pro-fibrotic phenotype. Mutated SMAD4 is found in many types of cancers and fibrosis.
The AlphaLISA SureFire Ultra Human and Mouse Total SMAD4 Detection Kit is a sandwich immunoassay for the quantitative detection of total SMAD4 in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Points |
500
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
Mouse
|
Therapeutic Area |
Metabolic
Oncology
|
Unit Size |
500 Assay Points
|
This guide outlines further possible optimization of cellular and immunoassay parameters to ensure the best possible results are...
Discover Alpha SureFire® Ultra™ assays, the no-wash cellular kinase assays leveraging Revvity's exclusive bead-based technology...
Therapeutic antibodies directed to cell surface receptors are increasingly being developed as treatments for a variety of diseases...
The measurement of protein phosphorylation is a useful tool for measuring the modulation of receptor activation by both antibodies...
Are you looking for technical documents for this product. We have housed them in a dedicated section., click on the links below to explore.
We are here to answer your questions.