The AlphaLISA® SureFire® Ultra™ Human and Mouse Total RNA POL II assay is a sandwich immunoassay for quantitative detection of total RNA POL II in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
RNA Polymerase II, also known as RNAP II and Pol II, is one of three RNA polymerase enzymes found in the nucleus of eukaryotic cells. Pol II is responsible for unspooling the genetic program in the form of protein-coding mRNAs and some small non-coding RNAs. A wide range of transcription factors are required for Pol II to bind to upstream gene promoters and begin transcriptions. Inhibitors targeting Pol II transcription machinery are potential therapeutics in various cancers and complex diseases.
The AlphaLISA SureFire Human and Mouse Total RNA POL II Detection Kit is a sandwich immunoassay for the quantitative detection of total RNA POL II in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Target Species |
Human
Mouse
|
Therapeutic Area |
Oncology
|
Unit Size |
100 Assay Points
|
This guide outlines further possible optimization of cellular and immunoassay parameters to ensure the best possible results are...
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