The AlphaLISA™ SureFire® Ultra™ Human and Mouse Total RBM39 assay is a sandwich immunoassay for quantitative detection of total RBM39 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Feature | Specification |
---|---|
Application | Cell Signaling |
Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Human and Mouse Total RBM39 assay is a sandwich immunoassay for quantitative detection of total RBM39 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
RNA binding motif protein 39 (RBM39), also known as CAPERα, HCC1, and RNPC2, is an RNA binding protein (RBP) and splicing factor that plays a role in maintaining transcript variant homeostasis. RBM39 promotes exon inclusion via regulation of exon cassette splicing and is a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha, ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity. RBM39 has been deemed essential for cancer cell survival and is associated with acute myeloid leukemia (AML), myeloma malignancy, breast cancer, and lung cancer.
The AlphaLISA SureFire Human and Mouse Total RBM39 Detection Kit is a sandwich immunoassay for the quantitative detection of total RBM39 in cellular lysates, using Alpha Technology.
Application |
Cell Signaling
|
---|---|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Modality |
Alpha
|
Lysis Buffer Compatibility |
Lysis Buffer
|
Molecular Modification |
Total
|
Product Group |
Kit
|
Sample Volume |
10 µL
|
Shipping Conditions |
Shipped in Blue Ice
|
Target |
RBM39
|
Target Class |
Phosphoproteins
|
Target Species |
Human
Mouse
|
Technology |
Alpha
|
Therapeutic Area |
Oncology
|
Unit Size |
10,000 Assay Points
|
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