The AlphaLISA® SureFire® Ultra™ Human and Mouse Total RAB10 assay is a sandwich immunoassay for quantitative detection of total RAB10 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
RAS-related protein Rab10 (RAB10) belongs to the RAS superfamily of small GTPases. RAB10 is a key regulator of intracellular membrane trafficking by orchestrating the biogenesis, transport, tethering, and fusion of membrane-bound organelles and vesicles. LRRK2-mediated phosphorylation may cause deficits in endolysosomal trafficking pathways modulated by RAB10, contributing to neurodegenerative disease onset. RAB10 is associated with Alzheimer’s disease and Parkinson’s disease.
The AlphaLISA SureFire Ultra Human and Mouse Total RAB10 assay is a sandwich immunoassay for the quantitative detection of total RAB10 in cellular lysates, using Alpha Technology.
Application |
Protein Detection
|
---|---|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Target Species |
Human
Mouse
|
Therapeutic Area |
Central Nervous System
|
Unit Size |
500 Assay Points
|
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