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AlphaLISA SureFire Ultra Human & Mouse Total RAB8A Detection Kit, 500 Assay Points
AlphaLISA SureFire Ultra Human & Mouse Total RAB8A Detection Kit, 500 Assay Points
The AlphaLISA™ SureFire® Ultra™ Human and Mouse Total RAB 8A assay is a sandwich immunoassay for quantitative detection of total RAB 8A in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
| Feature | Specification |
|---|---|
| Application | Cell Signaling |
| Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Human and Mouse Total RAB 8A assay is a sandwich immunoassay for quantitative detection of total RAB 8A in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
AlphaLISA SureFire Ultra Human & Mouse Total RAB8A Detection Kit, 500 Assay Points
AlphaLISA SureFire Ultra Human & Mouse Total RAB8A Detection Kit, 500 Assay Points
Product information
Overview
Ras-related protein RAB8A is a member of the RAS superfamily, which consists of small GTP/GDP binding proteins. Small GTPases Rab are key regulators of intracellular membrane trafficking, including the formation of transport vesicles to their fusion with membranes. RAB8A is involved in polarized vesicular trafficking and neurotransmitter release. RAB8A is associated with selective autophagy. Rab8a is one of several Rab GTPases that are substrates of leucine-rich repeat kinase 2 (LRRK2), a serine/threonine kinase that is linked to Parkinson's disease.
The AlphaLISA SureFire Human and Mouse Total RAB 8A Detection Kit is a sandwich immunoassay for the quantitative detection of total RAB 8A in cellular lysates, using Alpha Technology.
Formats
- The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
- The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
- The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
- The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
AlphaLISA SureFire Ultra kits are compatible with
- Cell and tissue lysates
- Antibody modulators
- Biotherapeutic antibodies
Alpha SureFire kits can be used for
- Cellular kinase assays
- Receptor activation studies
- Screening
Specifications
| Application |
Cell Signaling
|
|---|---|
| Automation Compatible |
Yes
|
| Brand |
AlphaLISA SureFire Ultra
|
| Detection Modality |
Alpha
|
| Lysis Buffer Compatibility |
Lysis Buffer
|
| Molecular Modification |
Total
|
| Product Group |
Kit
|
| Sample Volume |
10 µL
|
| Shipping Conditions |
Shipped in Blue Ice
|
| Target |
RAB 8A
|
| Target Class |
Phosphoproteins
|
| Target Species |
Human
Mouse
|
| Technology |
Alpha
|
| Therapeutic Area |
Neuroscience
|
| Unit Size |
500 Assay Points
|
Video gallery
AlphaLISA SureFire Ultra Human & Mouse Total RAB8A Detection Kit, 500 Assay Points
AlphaLISA SureFire Ultra Human & Mouse Total RAB8A Detection Kit, 500 Assay Points
Resources
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