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AlphaLISA SureFire Ultra Human Total PKR Detection Kit, 10,000 Assay Points

The AlphaLISA™ SureFire® Ultra™ Human Total PKR assay is a sandwich immunoassay for quantitative detection of total PKR in cellular lysates using Alpha Technology.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).

Feature Specification
Application Cell Signaling
Sample Volume 10 µL

The AlphaLISA™ SureFire® Ultra™ Human Total PKR assay is a sandwich immunoassay for quantitative detection of total PKR in cellular lysates using Alpha Technology.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).

Product Variants
Unit Size: 500 Assay Points
Part #:
ALSU-TPKR-A500
List Price
USD 2,346.00
Unit Size: 10,000 Assay Points
Part #:
ALSU-TPKR-A10K
List Price
USD 14,270.00
Unit Size: 50,000 Assay Points
Part #:
ALSU-TPKR-A50K
List Price
USD 46,060.00
Unit Size: 100 Assay Points
Part #:
ALSU-TPKR-A-HV
List Price
USD 694.44

Overview

Protein kinase R (PKR) is a kinase encoded by the EIF2AK2 gene and is involved in central cellular processes such as mRNA translation, transcriptional control, regulation of apoptosis, and proliferation. PKR plays a key role in the innate immunity pathway and is a mediator of the antiviral effects exerted by interferons. PKR also regulates eIF2α through phosphorylation. Dysregulation of PKR has been implicated in cancer, neurodegenerative disease, inflammation, and metabolic disorders.

The AlphaLISA SureFire Ultra Human Total PKR assay is a sandwich immunoassay for the quantitative detection of total PKR in cellular lysates, using Alpha Technology.

Formats:
  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
AlphaLISA SureFire Ultra kits are compatible with:
  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies
Alpha SureFire kits can be used for:
  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Application
Cell Signaling
Automation Compatible
Yes
Brand
AlphaLISA SureFire Ultra
Detection Modality
Alpha
Lysis Buffer Compatibility
Lysis Buffer
Molecular Modification
Total
Product Group
Kit
Sample Volume
10 µL
Shipping Conditions
Shipped in Blue Ice
Target
PKR
Target Class
Phosphoproteins
Target Species
Human
Technology
Alpha
Therapeutic Area
Central Nervous System
Metabolic
Oncology
Unit Size
10,000 Assay Points

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Alpha SureFire Ultra no-wash immunoassay catalog

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