The AlphaLISA™ SureFire® Ultra™ Human and Mouse Total PERK assay is a sandwich immunoassay for quantitative detection of total PERK in cellular lysates using Alpha Technology.
Please note that the Total PERK assay is distinct from the Total ERK1/2 assay.
The Total PERK assay contains antibodies which recognize distinct epitopes on PERK.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Protein kinase-like endoplasmic reticulum kinase (PERK) is an eIF2α kinase and transmembrane protein that resides in the endoplasmic reticulum (ER) membrane and is activated upon ER stress signals. PERK activation during ER stress correlates with autophosphorylation of its cytoplasmic kinase domain. Phosphorylation of PERK at Thr980 serves as a marker for its activation status. PERK promotes tumor growth by limiting oxidative DNA damage and is associated with neurodegenerative diseases and many cancers.
The AlphaLISA SureFire Human and Mouse Total PERK Detection Kit is a sandwich immunoassay for the quantitative detection of total PERK in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Points |
500
|
Assay Target |
PERK
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
Mouse
|
Therapeutic Area |
Neuroscience
Oncology
|
Unit Size |
500 Assay Points
|
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