The AlphaLISA™ SureFire® Ultra™ Human Total p300 assay is a sandwich immunoassay for quantitative detection of total p300 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Histone acetyltransferase p300 is an acetyl transferase encoded by the EP300 gene with numerous aliases: p300, p300 HAT, E1A-associated protein p300 (where E1A = adenovirus early region 1A), and EP300. p300 mediates histone 3 lysine 27 acetylation (H3K27ac) at regulatory elements such as enhancers and promoters. p300 is over-expressed in cancer cells and drug-resistant cancer cells, it activates oncogene transcription and induces cancer cell proliferation, survival, tumorigenesis, metastasis, immune evasion, and drug-resistance.
The AlphaLISA SureFire Human Total p300 Detection Kit is a sandwich immunoassay for the quantitative detection of total p300 in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Target |
p300
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
|
Therapeutic Area |
Oncology
|
Unit Size |
500 Assay Points
|
This guide outlines further possible optimization of cellular and immunoassay parameters to ensure the best possible results are...
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