The AlphaLISA™ SureFire® Ultra™ Human Phospho-Nrf2 (Ser40) assay is a sandwich immunoassay for quantitative detection of phospho-Nrf2 (Ser40) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Nuclear factor erythroid 2-related factor 2 (Nrf2), also known as nuclear factor erythroid-derived 2-like 2, is a basic leucine zipper (bZIP) encoded by the NFE2L2 gene. Based on preliminary research, Nrf2 may regulate the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation. NRF2 is thought to play a pleiotropic function in the control of metabolism, inflammation, autophagy, proteostasis, mitochondrial physiology, and immunological responses. For the treatment of illnesses brought on by oxidative stress, numerous medications that promote the NRF2 pathway are being investigated.
The AlphaLISA SureFire Human Phospho-Nrf2 (Ser40) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-Nrf2 (Ser40) in cellular lysates, using Alpha Technology.
Application |
Protein Detection
|
---|---|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
|
Therapeutic Area |
Autoimmunity
Immuno-oncology
Inflammation
|
Unit Size |
500 Assay Points
|
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