The AlphaLISA™ SureFire® Ultra™ Human Total NPM assay is a sandwich immunoassay for quantitative detection of total NPM in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Feature | Specification |
---|---|
Application | Cell Signaling |
Sample Volume | 30 µL |
The AlphaLISA™ SureFire® Ultra™ Human Total NPM assay is a sandwich immunoassay for quantitative detection of total NPM in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Nucleophosmin (NPM, Nucleolar Phosphoprotein B23, No38, or Numatrin) is a highly conserved, abundant nucleolar protein found in the nuclei of proliferating cells. NPM is a chaperone protein that shuttles rapidly between the nucleus and cytoplasm. It plays key roles in ribosome biogenesis, centrosome duplication, genomic stability, cell cycle progression, and apoptosis. NPM overexpression, mutation, rearrangement, or deletion, is associated with several types of cancer.
The AlphaLISA SureFire Human Total NPM Detection Kit Detection Kit is a sandwich immunoassay for the quantitative detection of total NPM in cellular lysates, using Alpha Technology.
Application |
Cell Signaling
|
---|---|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Modality |
Alpha
|
Lysis Buffer Compatibility |
Lysis Buffer
|
Molecular Modification |
Total
|
Product Group |
Kit
|
Sample Volume |
30 µL
|
Shipping Conditions |
Shipped in Blue Ice
|
Target |
NPM
|
Target Class |
Phosphoproteins
|
Target Species |
Human
|
Technology |
Alpha
|
Therapeutic Area |
Oncology
|
Unit Size |
100 Assay Points
|
Are you looking for resources, click on the resource type to explore further.
Therapeutic antibodies directed to cell surface receptors are increasingly being developed as treatments for a variety of diseases...
The measurement of protein phosphorylation is a useful tool for measuring the modulation of receptor activation by both antibodies...
We are here to answer your questions.