The AlphaLISA® SureFire® Ultra™ Human and Mouse Phospho-LRRK2 (Ser955) assay is a sandwich immunoassay for quantitative detection of phospho-LRRK2 (Ser955) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Leucine-rich repeat kinase 2 (LRRK2, Dardarin, or PARK8) is a large, multifunctional kinase enzyme, classified as a member of the ROCO superfamily. The ROCO family is characterized by the presence of tandem Ras of complex (Roc) G-domain, kinase domains, and carboxy- terminal of Roc (COR) sequence which links them. LRRK2 plays a role in lysosomal function and the innate immunity in the brain (microglia activation) and modulates Tau phosphorylation via GSK-3b. Mutations in LRRK2 are associated with Parkinson’s disease.
The AlphaLISA SureFire Human and Mouse Phospho-LRRK2 (Ser955) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-LRRK2 (Ser955) in cellular lysates, using Alpha Technology.
Application |
Protein Detection
|
---|---|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Target Species |
Human
Mouse
|
Therapeutic Area |
Neuroscience
|
Unit Size |
100 Assay Points
|
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