The AlphaLISA™ SureFire® Ultra™ Total IRF3 assay is a sandwich immunoassay for quantitative detection of total IRF3 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Interferon regulatory factor 3 (IRF3) is a part of the IRF family which is involved in the regulation of interferon α and β and play a role in host anti-viral immune regulation, cell growth, and hematopoietic development. In viral infected cells, phosphorylation of transcription factor IRF3 induces the production of antiviral and proinflammatory cytokines, a key element in the type 1 interferon-independent innate immune response. IRF3 is activated downstream of the STING signaling pathway and toll-like receptor signaling pathway. IRF3 is associated with cancer and autoinflammatory disease.
The AlphaLISA SureFire Ultra Total IRF3 assay is a sandwich immunoassay for the quantitative detection of total IRF3 in cellular lysates, using Alpha Technology.
Formats:
AlphaLISA SureFire Ultra kits are compatible with:
Alpha SureFire kits can be used for:
Application |
Protein Analysis & Detection
Protein Detection
Target Engagement
|
---|---|
Assay Target |
IRF3
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Shipping Conditions |
Shipped in Blue Ice
|
Therapeutic Area |
Autoimmunity
Oncology
|
Unit Size |
10,000 Assay Points
|
This guide outlines further possible optimization of cellular and immunoassay parameters to ensure the best possible results are...
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