The AlphaLISA™ SureFire® Ultra™ Human Total IKKβ assay is a sandwich immunoassay for quantitative detection of total IKKβ in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Inhibitor of nuclear factor kappa-B kinase subunit β (IKKβ) is a protein subunit of IkB kinase, which is an enzyme complex involved in propagating cellular response to inflammation. Activated IKKβ phosphorylates IkBα, preventing IkBα from inhibiting NF-kB which then frees NF-kB and allows it to enter the nucleus of the cell, where it activates various genes involved in inflammation and other immune responses. The IKKβ signaling pathway is associated with numerous therapeutic areas, including diseases such as multiple sclerosis, rheumatoid arthritis, psoriasis, and many types of cancers.
The AlphaLISA SureFire Ultra Human Total IKKβ Detection Kit is a sandwich immunoassay for the quantitative detection of total IKKβ in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Points |
500
|
Assay Target |
IKKβ
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
|
Therapeutic Area |
Autoimmunity
Immuno-oncology
Oncology
|
Unit Size |
500 Assay Points
|
Therapeutic antibodies directed to cell surface receptors are increasingly being developed as treatments for a variety of diseases...
The measurement of protein phosphorylation is a useful tool for measuring the modulation of receptor activation by both antibodies...
Are you looking for technical documents related to the product? We have categorized them in dedicated sections below. Explore now.
We are here to answer your questions.