The AlphaLISA™ SureFire® Ultra™ Human Phospho-IKKβ (Ser177/181) assay is a sandwich immunoassay for quantitative detection of phospho-IKKβ (Ser177/181) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Inhibitor of nuclear factor kappa-B kinase subunit β (IKKβ) is a protein subunit of IkB kinase, which is an enzyme complex involved in propagating cellular response to inflammation. Activated IKKβ phosphorylates IkBα, preventing IkBα from inhibiting NF-kB which then frees NF-kB and allows it to enter the nucleus of the cell, where it activates various genes involved in inflammation and other immune responses. The IKKβ signaling pathway is associated with numerous therapeutic areas, including diseases such as multiple sclerosis, rheumatoid arthritis, psoriasis, and many types of cancers.
The AlphaLISA SureFire Ultra Human Phospho-IKKβ (Ser177/181) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-IKKβ (Ser177/181) in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Points |
50000
|
Assay Target |
IKKβ
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
|
Therapeutic Area |
Autoimmunity
Immuno-oncology
Oncology
|
Unit Size |
50,000 Assay Points
|
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