The AlphaLISA™ SureFire® Ultra™ Human Total RIP3 assay is a sandwich immunoassay for quantitative detection of total RIP3 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Feature | Specification |
---|---|
Application | Cell Signaling |
Sample Volume | 30 µL |
The AlphaLISA™ SureFire® Ultra™ Human Total RIP3 assay is a sandwich immunoassay for quantitative detection of total RIP3 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) is a critical regulator of programmed necroptosis, an inflammatory form of cell death with important functions in pathogen-induced and sterile inflammation. RIP3 mediates necroptosis in conjunction with RIPK1 and MLKL. Due to the inflammation caused by necroptosis, RIPK3 is associated with a variety of inflammatory diseases.
The AlphaLISA SureFire Ultra Human Total RIP3 assay is a sandwich immunoassay for the quantitative detection of total RIP3 in cellular lysates, using Alpha Technology.
Application |
Cell Signaling
|
---|---|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Modality |
Alpha
|
Lysis Buffer Compatibility |
Lysis Buffer
|
Molecular Modification |
Total
|
Product Group |
Kit
|
Sample Volume |
30 µL
|
Shipping Conditions |
Shipped in Blue Ice
|
Target |
RIP3
|
Target Class |
Phosphoproteins
|
Target Species |
Human
|
Technology |
Alpha
|
Therapeutic Area |
Autoimmunity
Central Nervous System
Neuroinflammation
|
Unit Size |
100 Assay Points
|
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