The AlphaLISA™ SureFire® Ultra™ Human Total GCN2 assay is a sandwich immunoassay for quantitative detection of total GCN2 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
General control nonderepressible 2 (GCN2) is a serine/threonine-protein kinase that plays a key role in modulating amino acid metabolism as a response to nutrient deprivation. GCN2 is one of the four known sensors of the integrated stress response (ISR), which is a cytoprotective response mediated by eIF2α. Under conditions of amino acid deprivation, GCN2 inactivates eIF2α by phosphorylation, and eIF2α phosphorylation can also lead to enhanced transcription of mRNA molecules involved in host response to infection and inflammation. GCN2 is associated with cancer.
The AlphaLISA SureFire Ultra Human Total GCN2 assay is a sandwich immunoassay for the quantitative detection of total GCN2 in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Target |
GCN2
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
|
Therapeutic Area |
Oncology
|
Unit Size |
500 Assay Points
|
Discover Alpha SureFire® Ultra™ assays, the no-wash cellular kinase assays leveraging Revvity's exclusive bead-based technology...
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