The AlphaLISA™ SureFire® Ultra™ Human Phospho-FOXM1 (Thr600) assay is a sandwich immunoassay for quantitative detection of phospho-FOXM1 (Thr600) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Forkhead box protein M1 (FOXM1) is a transcription factor expressed throughout the cell cycle, rising in late G1-phase, reaching its apex in S-phase, and remaining there in G2/M and late M-phase. FOXM1 plays a significant role in multiple key cell cycle phases and is known as the master regulator of the cell cycle. The transcriptional network associated with FOXM1 regulates many processes, including stemness, cell survival, DNA damage repair, DNA replication, cell G1/S transition, cell cycle, cell proliferation, clonal formation, migration capacity, invasion, metastasis, and tumor initiation and progression. FOXM1 is found to be overexpressed in numerous malignancies such as breast, colorectal, hepatocellular, ovarian, lung, and pancreatic cancers.
The AlphaLISA SureFire Human Phospho-FOXM1 (Thr600) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-FOXM1 (Thr600) in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Target |
FOXM1
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
|
Therapeutic Area |
Oncology
|
Unit Size |
10,000 Assay Points
|
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