The AlphaLISA™ SureFire® Ultra™ Human Phospho-FLT3 (Tyr591) assay is a sandwich immunoassay for quantitative detection of phospho-FLT3 (Tyr591) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Fms related receptor tyrosine kinase 3 (FLT3) is a member of the class III receptor kinase family. FLT3 acts as a cell surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and of dendritic cells. This kinase is involved in the activation of the downstream effort of MTOR, promotes activation of RAS signaling, and phosphorylates downstream kinases including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations of the FLT3 gene occur in approximately 30% of all acute myeloid leukemia cases.
The AlphaLISA SureFire Human Phospho-FLT3 (Tyr591) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-FLT3 (Tyr591) in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Points |
500
|
Assay Target |
FLT3
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
|
Therapeutic Area |
Oncology
|
Unit Size |
500 Assay Points
|
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