The AlphaLISA™ SureFire® Ultra™ Human Phospho-Estrogen Receptor α (ERα) (Ser167) assay is a sandwich immunoassay for quantitative detection of phospho-ERα (Ser167) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Estrogen Receptors (ERs) are a group of proteins found inside cells and exist in two classes: ERα and ERβ. ERs are activated by estrogen and are able to translocate into the nucleus and bind to DNA to regulate the activity of different genes, but also have functions independent of DNA binding. ERs are expressed in >70% of all breast cancers with ERα being the main target in clinical approaches for controlling hormonally responsible breast cancer. ERα is associated with a variety of other cancers, including prostate, liver, and pancreatic ductal adenocarcinoma.
The AlphaLISA SureFire Ultra Human Phospho-ERα (Ser167) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-ERα (Ser167) in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Points |
500
|
Assay Target |
ERα
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
|
Therapeutic Area |
Oncology
|
Unit Size |
500 Assay Points
|
This guide outlines further possible optimization of cellular and immunoassay parameters to ensure the best possible results are...
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