The AlphaLISA™ SureFire® Ultra™ Human Total CD3 ζ assay is a sandwich immunoassay for quantitative detection of total CD3 ζ in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Feature | Specification |
---|---|
Application | Cell Signaling |
Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Human Total CD3 ζ assay is a sandwich immunoassay for quantitative detection of total CD3 ζ in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Cluster of differentiation 3 Zeta (CD3 ζ) also known as T-cell receptor T3 zeta chain or CD247, is one of the four chains composing the CD3 complex. CD3 is a T-cell co receptor involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of two CD3ε chains, a CD3γ chain, and a CD3δ chain. The Zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response.
The AlphaLISA SureFire Ultra Human Total CD3 ζ Detection Kit is a sandwich immunoassay for the quantitative detection of total CD3 ζ in cellular lysates, using Alpha Technology.
Application |
Cell Signaling
|
---|---|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Modality |
Alpha
|
Lysis Buffer Compatibility |
Lysis Buffer
|
Molecular Modification |
Total
|
Product Group |
Kit
|
Sample Volume |
10 µL
|
Shipping Conditions |
Shipped in Blue Ice
|
Target |
CD3 ζ
|
Target Class |
Phosphoproteins
|
Target Species |
Human
|
Technology |
Alpha
|
Therapeutic Area |
Autoimmunity
Immuno-oncology
Oncology
|
Unit Size |
50,000 Assay Points
|
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