AlphaLISA SureFire Ultra Human Phospho-c-Myb (Ser11) Detection Kit, 500 Assay Points

Mammalian oncogenic transcription factor c-Myb is a member of the MYB family of proteins, encoded by the C-MYB gene, which is located in chromosome 6. The family received its name because of its association with myeloblastosis, taking the letters ‘m’, ‘y’ and ‘b’ from this word to create the family name. C-myb controls several genes related to cell proliferation, differentiation, and apoptosis. Sustained and high levels of MYB expression are seen in leukemia, colon cancer, breast cancer, and adenoid cystic carcinoma.

The AlphaLISA SureFire Ultra Human Phospho-c-Myb (Ser11) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-c-Myb (Ser11) in cellular lysates, using Alpha Technology.

Formats:

• The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
• The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
• The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
• The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with:

• Cell and tissue lysates
• Antibody modulators
• Biotherapeutic antibodies

Alpha SureFire kits can be used for:

• Cellular kinase assays
• Receptor activation studies
• Screening