The AlphaLISA™ SureFire® Ultra™ Human and Mouse Phospho-c-Jun (Ser63) assay is a sandwich immunoassay for quantitative detection of phospho-c-Jun (Ser63) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
c-Jun belongs to the mammalian Jun protein family which are transcription factors that must dimerize to bind to their target DNA sites. c-Jun is a major component of the activator protein 1 (AP-1) complex. Phosphorylation of c-Jun at Ser63 and Ser73 through JNK stimulates AP-1. Once phosphorylated, c-Jun can dimerize and bind to DNA sequences and affect transcription. c-Jun regulates numerous cellular responses including proliferation, malignant transformation, differentiation, and apoptosis. C-Jun plays a role in many types of cancers and autoimmune diseases.
The AlphaLISA SureFire Human and Mouse Phospho-c-Jun (Ser63) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-c-Jun (Ser63) in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Points |
100
|
Assay Target |
c-Jun
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
Mouse
|
Therapeutic Area |
Autoimmunity
Oncology
|
Unit Size |
100 Assay Points
|
Discover Alpha SureFire® Ultra™ assays, the no-wash cellular kinase assays leveraging Revvity's exclusive bead-based technology...
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