The AlphaLISA™ SureFire® Ultra™ Human and Mouse Total BRD7 assay is a sandwich immunoassay for quantitative detection of total BRD7 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Feature | Specification |
---|---|
Application | Cell Signaling |
Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Human and Mouse Total BRD7 assay is a sandwich immunoassay for quantitative detection of total BRD7 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Bromodomain containing 7 (BRD7), also known as NAG4, BP75, or CELTIX1, is a member of the Bromodomain-containing Protein Family IV, which also includes BRD9. BRD7 plays a role in chromatin remodeling and regulation of transcription. Inhibition of BRD7 expression promotes cell proliferation and migration by activating ERK phosphorylation. Increasing evidence indicates that BRD7 is downregulated in many cancers, such as epithelial ovarian carcinoma, breast cancer, nasopharyngeal cancer, and colorectal carcinoma.
The AlphaLISA SureFire Human and Mouse Total BRD7 Detection Kit is a sandwich immunoassay for the quantitative detection of total BRD7 in cellular lysates, using Alpha Technology.
Application |
Cell Signaling
|
---|---|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Modality |
Alpha
|
Lysis Buffer Compatibility |
Lysis Buffer
|
Molecular Modification |
Total
|
Product Group |
Kit
|
Sample Volume |
10 µL
|
Shipping Conditions |
Shipped in Blue Ice
|
Target |
BRD7
|
Target Class |
Phosphoproteins
|
Target Species |
Human
Mouse
|
Technology |
Alpha
|
Therapeutic Area |
Oncology
|
Unit Size |
50,000 Assay Points
|
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