The AlphaLISA® SureFire® Ultra™ Total Beclin-1 assay is a sandwich immunoassay for quantitative detection of total Beclin-1 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Beclin-1 (BECN1) plays a central role in the regulation of autophagy and cell death. Together with PI3KC3, Beclin-1 nucleates autophagosome formation and is essential for proper degradation of cellular components. The activity of Beclin-1 is impacted by many factors, especially different binding partners. Numerous membranic, cytosolic, and nuclear proteins have been identified as activators of autophagy by binding to Beclin-1. Improper Beclin-1 signaling is associated with cancer, neurodegenerative diseases, and cardiac dysfunction.
The AlphaLISA SureFire Ultra Total Beclin-1 assay is a sandwich immunoassay for the quantitative detection of total Beclin-1 in cellular lysates, using Alpha Technology.
Formats:
AlphaLISA SureFire Ultra kits are compatible with:
Alpha SureFire kits can be used for:
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Therapeutic Area |
Cardiovascular
Oncology
|
Unit Size |
500 Assay Points
|
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