The AlphaLISA™ SureFire® Ultra™ Human and Mouse Total BCL-XL assay is a sandwich immunoassay for quantitative detection of total BCL-XL in cellular lysates using Alpha Technology.
B-cell lymphoma-extra large (BCL-XL) is a member of the BCL-2 protein family resulting in apoptosis inhibition or pro-survival function. Beclin 1, a key factor in autophagy regulation, interacts with BCL-XL. BCL-XL is also essential for the survival of neurons and is involved in protective roles in neuronal injuries. Numerous cancers and other diseases are associated with BCL-XL, including acute lymphoblastic leukemia, non-Hodgkin’s lymphoma, small cell lung cancer, breast cancer, gastric cancer, prostate cancer, and neurodegenerative disorders.
The AlphaLISA SureFire Human and Mouse Total BCL-XL Detection Kit is a sandwich immunoassay for the quantitative detection of total BCL-XL in cellular lysates, using Alpha Technology.
For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Target |
BCL-XL
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
Mouse
|
Therapeutic Area |
Neuroscience
Oncology
|
Unit Size |
500 Assay Points
|
This guide outlines further possible optimization of cellular and immunoassay parameters to ensure the best possible results are...
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