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AlphaLISA SureFire Ultra Human Phospho-BCL-2 (Ser70) Detection Kit, 10,000 Assay Points
AlphaLISA SureFire Ultra Human Phospho-BCL-2 (Ser70) Detection Kit, 10,000 Assay Points
The AlphaLISA™ SureFire® Ultra™ Human Phospho-BCL-2 (Ser70) assay is a sandwich immunoassay for quantitative detection of phospho-BCL-2 (Ser70) in cellular lysates using Alpha Technology.
For research use only. Not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption, and disposal requirements under European REACH regulations (EC 1907/2006).
| Feature | Specification |
|---|---|
| Application | Cell Signaling |
| Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Human Phospho-BCL-2 (Ser70) assay is a sandwich immunoassay for quantitative detection of phospho-BCL-2 (Ser70) in cellular lysates using Alpha Technology.
For research use only. Not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption, and disposal requirements under European REACH regulations (EC 1907/2006).
AlphaLISA SureFire Ultra Human Phospho-BCL-2 (Ser70) Detection Kit, 10,000 Assay Points
AlphaLISA SureFire Ultra Human Phospho-BCL-2 (Ser70) Detection Kit, 10,000 Assay Points
Product information
Overview
The oncogenic protein BCL-2 (B-cell lymphoma 2) is known for its role in preventing apoptosis. It is a 24-26 kDa protein that is found in the nuclear envelope, endoplasmic reticulum, and mitochondrial membrane. BCL-2 is categorized as a proto-oncogene since it is thought to be a significant antiapoptotic protein. Numerous cancers, such as breast, prostate, skin, colon, and pancreatic cancers, as well as neurological and autoimmune illnesses, have been linked to BCL-2 overexpression. The anti-apoptotic proteins BCL-XL, MCL-1, and BCL-W are all related. The BCL-2 family of proteins contains proapoptotic proteins such as Bax, BAD, Bak, Blk, and Bid.
The AlphaLISA SureFire Human Phospho-BCL-2 (Ser70) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-BCL-2 (Ser70) in cellular lysates, using Alpha Technology.
Formats:
- The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
- The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
- The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
- The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
AlphaLISA SureFire Ultra kits are compatible with:
- Cell and tissue lysates
- Antibody modulators
- Biotherapeutic antibodies
Alpha SureFire kits can be used for:
- Cellular kinase assays
- Receptor activation studies
- Screening
Specifications
| Application |
Cell Signaling
|
|---|---|
| Automation Compatible |
Yes
|
| Brand |
AlphaLISA SureFire Ultra
|
| Detection Modality |
Alpha
|
| Lysis Buffer Compatibility |
Lysis Buffer
|
| Molecular Modification |
Phosphorylation
|
| Product Group |
Kit
|
| Sample Volume |
10 µL
|
| Shipping Conditions |
Shipped in Blue Ice
|
| Target |
BCL-2
|
| Target Class |
Phosphoproteins
|
| Target Species |
Human
|
| Technology |
Alpha
|
| Therapeutic Area |
Oncology
|
| Unit Size |
10,000 Assay Points
|
Video gallery
AlphaLISA SureFire Ultra Human Phospho-BCL-2 (Ser70) Detection Kit, 10,000 Assay Points
AlphaLISA SureFire Ultra Human Phospho-BCL-2 (Ser70) Detection Kit, 10,000 Assay Points
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