The AlphaLISA™ SureFire® Ultra™ Human and Mouse Total Androgen Receptor assay is a sandwich immunoassay for quantitative detection of total Androgen Receptor in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Androgen Receptor (AR) is a type of nuclear receptor that is activated by androgen hormones, such as testosterone and dihydrotestosterone. Gene expression induced by AR results in cell division, proliferation, differentiation, apoptosis, and angiogenesis. Dysregulation of the AR pathway could lead to oncogenic phenotypes, and AR activation has been widely linked to prostate cancer as well as other types of cancer, like breast cancer and glioblastoma. The development of PROTAC compounds to target AR degradation is a part of the therapeutic strategy to target AR positive cancers.
The AlphaLISA SureFire Human and Mouse Total Androgen Receptor Detection Kit is a sandwich immunoassay for the quantitative detection of total Androgen Receptor in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Points |
500
|
Assay Target |
Androgen Receptor
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
Mouse
|
Therapeutic Area |
Oncology
|
Unit Size |
500 Assay Points
|
Therapeutic antibodies directed to cell surface receptors are increasingly being developed as treatments for a variety of diseases...
The measurement of protein phosphorylation is a useful tool for measuring the modulation of receptor activation by both antibodies...
Are you looking for technical documents related to the product? We have categorized them in dedicated sections below. Explore now.
We are here to answer your questions.