The AlphaLISA™ SureFire® Ultra™ Human Total AIOLOS assay is a sandwich immunoassay for quantitative detection of total AIOLOS in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Feature | Specification |
---|---|
Application | Cell Signaling |
Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Human Total AIOLOS assay is a sandwich immunoassay for quantitative detection of total AIOLOS in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
AIOLOS, also known as Ikaros family zinc finger protein 3, is a transcription factor encoded by the IKZF3 gene. Three members of this protein family (IKAROS, AIOLOS and HELIOS) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. Overexpression of Ikaros protein family members is associated with uncontrolled proliferation and survival of cancer cells and is associated with cancers such as malignant plasma cells and multiple myeloma.
The AlphaLISA SureFire Ultra Human Total AIOLOS Detection Kit is a sandwich immunoassay for the quantitative detection of total AIOLOS in cellular lysates, using Alpha Technology.
Formats:
AlphaLISA SureFire Ultra kits are compatible with:
Alpha SureFire kits can be used for:
Application |
Cell Signaling
|
---|---|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Modality |
Alpha
|
Lysis Buffer Compatibility |
Lysis Buffer
|
Molecular Modification |
Total
|
Predicted Species Reactivity |
Human
|
Product Group |
Kit
|
Sample Volume |
10 µL
|
Shipping Conditions |
Shipped in Blue Ice
|
Target |
AIOLOS
|
Target Class |
Phosphoproteins
|
Target Species |
Human
|
Technology |
Alpha
|
Therapeutic Area |
Oncology
|
Unit Size |
10,000 Assay Points
|
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