AB-MECA, labeled with 125I. AB-MECA acts as an agonist at adenosine A3 receptors, a group of GPCRs that are potential drug targets for immune-related disease, including rheumatoid arthritis, cancer, ischaemia, and inflammatory disease.
For research use only. Not for use in diagnostic procedures
50 µCi Quantities of AB-MECA, [125I]-(4-Amino-3-[125I]iodobenzyl-5`-N-)- are available for your research.
We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.
Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NEX312:
Molecular Weight |
523
|
---|
Application |
Drug Discovery & Development
|
---|---|
Brand |
NEN Radiochemicals
|
Detection Method |
Radiometric
|
Fresh Lot Days |
Second Monday of each month
|
Label Position |
Nominally Labeled
|
One Unit Contains |
50.0 µCi
|
Radionuclide |
125I
|
Radioisotope |
I-125
|
Receptor Type |
Adenosine
|
Shipping Conditions |
Shipped Ambient
|
Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
Therapeutic Area |
Cardiovascular
CNS & Neurologic
Inflammation
Metabolic Disorders
|
Unit Size |
50 µCi
|
Are you looking for technical documents related to the product? We have categorized them in dedicated sections below. Explore now.
We are here to answer your questions.