100 µCi Quantities of iodo-(±)-Cyanopindolol, [¹²⁵I], are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (B_max), dissociation constants (K_d), association and dissociation rates (k_on and k_off), and inhibitor constants (K_i) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX189:

1. Houseknecht, K., Bauman, D., Carey, G., Mersmann, H., (1995), Effect of bovine somatotropin and food deprivation on β-adrenergic and A1 adenosine receptor binding in adipose tissue of lactating cows, Domestic Animal Endocrinology, 12 (4): 325-336.
2. Mersmann, H., McNeel, R., Morkeberg, J., Shparber, A., Hachey, D., (1992), β-Adrenergic Receptor-Mediated Functions in Porcine Adipose Tissue Are Not Affected Differently by Saturated vs. Unsaturated Dietary Fats, The Journal of Nutrition, 122 (10): 1952–1959.