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Lentiviral high-throughput assay shows promise for identifying novel HIV-1 inhibitors
Lentiviral high-throughput assay shows promise for identifying novel HIV-1 inhibitors
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Targeting leishmaniasis with an entamoeba molecule
An immune-therapeutic approach to leishmaniasis treatment by targeting leishmaniasis with an entamoeba molecule.
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Gene editing of primary immune cells to aid next-generation cellular immunotherapies
Researchers have successfully deployed CRISPRa/i in primary human T cells, offering critical insights into the pathways required for cytokine regulation.
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Postbiotics: a paradigm shift in microbiome research
Investigating the impact of molecules produced by microbiota metabolism, known as postbiotics, on the human host
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A brand-new modality on the horizon: how targeted protein degradation can address the unmet need in drug discovery and development
Discover the potential of Targeted Protein Degradation (TPD) as an emerging drug discovery modality. Explore how TPD enables the selective targeting and degradation of proteins, even those previously considered "undruggable."
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Transforming cell therapies with dual CAR strategies
This white paper discusses the potential of dual CARs in transforming cell therapies.
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Conditional knockout generation using targeted exon excision and synthetic introns
This white paper explores approaches for conditional knockout generation using targeted exon excision and synthetic introns.
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Learning from our ancestors: can we be better prepared for the next pandemic?
Researchers have found evidence of an ancient viral epidemic involving host coronavirus interacting genes in East Asia more than 20,000 years ago. These findings could help countries prepare for future pandemics.
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Bioluminescence Resonance Energy Transfer (BRET) to monitor protein-protein interactions
The ability to image PPIs in vivo has important implications for a wide variety of biological research endeavors, including drug discovery and molecular medicine.
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Non-invasive optical imaging for viral research and novel therapeutic and vaccine development
Non-invasive optical image using IVIS ® systems for pre-clinical viral research.
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Cell-based assays: Purposeful screens for better results
Insights gained over the years through close interactions with researchers to provide the key elements to consider when setting up cell-based assays.
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KRAS biomarker becomes a target of choice in certain cancer therapies
Get the latest insights on KRAS and see how it has switched from being an undruggable to a druggable cancer target
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