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Brochure
IVIS Spectrum 2 platform - illumination in focus
Discover the next generation in preclinical optical imaging, the IVIS Spectrum 2 and IVIS SpectruCT 2 systems.
Case Study
Assessment of MYC-driven progression of small cell lung cancer
Researchers at Huntsman Cancer Center use GEMM and the Quantum microCT system for evaluating small cell lung cancer.
Literature - Publication Review
Biopolymers Codelivering Engineered T Cells and STING Agonists can Eliminate Heterogenous Tumors
Using the IVIS® Spectrum non-invasive preclinical optical system to quantify tumor-specific T cells responses in NFAT-luciferase transgenic mice.
Case Study
Optical and microCT imaging enables noninvasive monitoring of EBV-induced neuroinvasion
Researchers use optical and microCT imaging to noninvasively monitor EBV-induced neuroinvasion in a mouse model.
Literature - Publication Review
DNA origami elevates the design of multispecific antibodies as cancer therapeutic agents
Publication review highlighting the use of the IVIS™ Lumina X5 optical imaging system and BioLegend Antibodies describe programmable T cell engagers (PTEs), a novel class of agents created with DNA origami, a nanotechnology that allows the precise spatial arrangement of biomolecules. When combined with antibodies, this approach holds great promise to develop specific and effective biomedical nanotherapies for diseases like cancer.
Whitepaper
Establishing an automated high-throughput assay that supports the growth of prostate cancer organoids
Researchers concluded that their study demonstrates the ability to automate preclinical testing with prostate cancer organoids with diverse phenotypes.
Case Study
A novel mouse model using optical imaging to detect on-target, off-tumor CAR-T cell toxicity
A Novel Mouse Model Using IVIS® Optical Imaging to Detect On-Target, Off-Tumor CAR-T Cell Toxicity.
Whitepaper
Genetically engineered PDX models as patient avatars in preclinical evaluation of acute leukemias
Identifying therapeutic targets using gene silencing techniques in PDX models
Application Note
Imaging oncolytic virus infection in cancer cells
IVIS ® optical imaging to assess and quantify oncolytic viral infection in living tumors and the subsequent virus-host interactions in real-time.
Literature - Publication Review
Evaluating a novel nanoparticle platform for controlled liraglutide release in a Type II diabetes mouse model
Optical imaging using the IVIS® Platform to evaluate a novel nanoparticle system for controlled liraglutide release in a diabetic mouse model.
Case Study
Using IVIS optical imaging of CRISPR/Cas9 engineered adipose tissue to study obesity prevention
Assessment of brown fat activation of CRISPR engineered adipose tissue in a mouse model using Revvity's IVIS® optical imaging platform.
Literature - Publication Review
Improving engineered T cell efficacy for treating solid tumors through epigenetic modulation
Researchers used the Opera Phenix® HCS and IVIS® preclicinal imaging system to evaluate engineered T-cells through epigenetic modulation showing the potential of improving the cytotoxic effects on solid tumors.
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