IVIS Spectrum 2 In Vivo Imaging System

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IVIS Spectrum 2 In Vivo Imaging System

This product replaces the IVIS Spectrum system (part number 124262).

As the leader in optical imaging with thousands of publications using our flagship IVIS® Spectrum platform, the IVIS Spectrum 2 system is the next generation in optical imaging. Designed with an innovative camera with patented coating that delivers high sensitivity 2D and 3D bioluminescence and fluorescence imaging capabilities - the IVIS Spectrum 2 gives you the flexibility you need for your in vivo imaging studies.

For research use only. Not for use in diagnostic procedures.

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Product Variant

Imaging Modality: 2D and 3D Bioluminescence, 2D and 3D Fluorescence

Part #:

CLS158738

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Product information

Overview

Building upon the IVIS Spectrum in vivo optical system with proven 2D bioluminescence and 2D fluorescence imaging and 3D optical tomography capabilities combined in a single system, the IVIS Spectrum 2 is our next generation in optical imaging. This advanced imaging system incorporates a CCD camera with eXcelon® coating that enables detection of more signal at higher efficiency across a broader spectrum of wavelengths. With exclusivity to this innovative camera for in vivo imaging, the IVIS Spectrum 2 preclinical optical imaging system delivers the sensitivity you demand for non-invasive longitudinal imaging to better understand early disease-related biological changes, track disease progression, and help guide the drug development process.

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Features and benefits

High sensitivity

Exclusivity to patented CCD camera with eXcelon coating for high sensitivity imaging

Rapid Imaging

Rapid imaging

Fast data acquisition allows quick visualization of images in real-time

High Throughput

High throughput

Standard 5 mice configuration or up to 10 mice capacity using optional manifold

Trans-illumination

Imaging below the specimen for sensitive detection and quantification of deep fluorescent sources

Epi-illumination

Imaging above the specimen ideal for high throughput workflow

Co-registration

Seamless co-registration of optical data with other modalities, e.g., CT, MRI, SPECT, PET, Ultrasound

Spectral Unmixing

Spectral unmixing

Remove autofluorescence & easily identify, separate, and quantify multiplexed fluorescent signals

Analysis Software

Analysis software

Broadly adopted, easy to use, and intuitive, Living Image^® visualization and analysis software

Complimentary Living Image™ software licenses are provided with the IVIS systems and upon request.

High-performance CCD camera

The camera and coating facilitate detection of more signal at higher efficiency across a broader spectrum of wavelengths throughout the visible and NIR spectrum - giving you:

Improved signal-to-noise ratio for both bioluminescent and fluorescent signals
Increased bandwidth to encompass a wider range of NIR fluorescent probes

Camera highlights

Patented eXcelon® coating
Back-illuminated, thermoelectrically cooled (-90°C) CCD
High quantum efficiency (peak >95%)
2048 x 2048 imaging pixels with 13.5 micron pixel size
Low read noise

Bring your in vivo images to life with Living Image software

Broadly adopted imaging software that sets the industry standard for ease of use and flexibility

Comprehensive set of tools for 2D and 3D data analysis
One click 3D reconstructions
Spectral unmixing algorithms to easily obtain and separate simultaneous fluorescent readouts or remove unwanted autofluorescence
Co-register optical imaging with other modalities (e.g., CT, MRI, SPECT, PET)
Auto settings for easy image acquisition
Batch processing analysis tools
Generation of animated movies and publication ready figures
Flexible remote review for convenient offline analysis of data sets
Included in IVIS purchase

Which IVIS system is best for your research?

	IVIS spectrum 2	IVIS spectrumCT 2	IVIS lumina S5	IVIS lumina X5	IVIS lumina III	IVIS lumina LT	IVIS lumina XRMS
Capacity	Up to 10 mice*	Up to 10 mice*	Up to 10 mice*	Up to 10 mice*	Up to 5 mice**	Up to 5 mice**	Up to mice
Benchtop format			✔	✔	✔	✔	✔
2D Bioluminescence / Fluorescence	✔/✔	✔/✔	✔/✔	✔/✔	✔/✔	✔/✔	✔/✔
3D Bioluminescence / Fluorescence	✔/✔	✔/✔
Enhanced Fluorescence capabilities	✔	✔	✔	✔	✔		✔
Integrated standard x-ray							✔
Integrated high resolution x-ray				✔
Integrated CT		✔
Optical FOV (cm) (Nominal)	4-22.5	4-22.5	10-22.5	10-22.5	5-12(2.6**)	5-12(2.6**)	5-12
Wavelength range (nm)	415-850	415-850	410-865	410-865	410-865	415-875	410-865
For additional comparison information please refer to the IVIS Comparison flyer under the ‘Resources’ tab Using optional manifold kit *Using expansion lens