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Literature - Publication Review
Improving precision stratification using patient-derived model systems
Precision stratification using patient-derived model systems.
Whitepaper
Therapeutic targeting of the tumor microenvironment
Understanding How Tumor and Host Cells Interact to Support Tumor Development and Therapeutic Resistance
Whitepaper
Lentiviral high-throughput assay shows promise for identifying novel HIV-1 inhibitors
Lentiviral high-throughput assay shows promise for identifying novel HIV-1 inhibitors
Literature - Publication Review
The modulatory effects of A2AR on NMDAR functionality using primary neurons and microglia cultures for potential neuroprotection in Alzheimer’s disease
Neurodegenerative Diseases Therapies; CNS Research, A2AR, Alzheimer's Disease, NMDAR, Acetylcholinesterase inhibitors
Application Note
Measuring FRET using the Opera™ Phenix™ high-content screening system
Here, we present a FRET-based high-content screening assay to study the interaction of the anti-apoptotic protein Bcl-XL with the pro-apoptotic protein Bad.
Application Note
Imaging bile canaliculi in 3D liver microtissues
Here, we describe a 3D HCS assay to study hepatobiliary transporter function in InSphero human liver microtissues using the Opera Phenix™ HCS system.
Whitepaper
Targeting leishmaniasis with an entamoeba molecule
An immune-therapeutic approach to leishmaniasis treatment by targeting leishmaniasis with an entamoeba molecule.
Whitepaper
Addressing the challenges of bispecific antibody characterization with high-throughput platforms
With the complexities of bispecific antibody development and characterization explore the binding assays and technology through real-world examples
Literature - Publication Review
Unlocking the potential of cancer immunotherapy: Overcoming the challenges of 3D immune cell killing assays
Explore several successful assay setups that utilize various analysis technologies to study the antitumor functions of immunotherapies in a 3D environment.
Application Note
Label-free analysis of cardiomyocyte beating using the Opera Phenix Plus System
Learn how to reliable quantify cardiomyocyte beating frequency using the Opera Phenix Plus high-content screening system in this application note.
Application Note
Phenotypic analysis of CRISPR-Cas9 cell-cycle knockouts using cell painting
Learn about our harmonized workflow for morphological profiling of CRISPR-Cas9-mediated knockouts using cell painting in this Application Note.
Application Note
Phenotypic profiling of autophagy using high content profiler
Using an autophagy assay as an example, this study describes the validation of a phenotypic image and data analysis workflow.
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