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Application Note
CDK signaling: Investigate CDK4/6 inhibition in breast cancer cell lines with HTRF immunoassays
Learn how to analyze the inhibition of CDK4 and CDK9 in breast cancer using no-wash immunoassays.
Application Note
HTRF platform for anticancer drug discovery: from 2D and 3D cell cultures to xenograft models
Learn how to analyze cell signaling pathways on in vitro and in vivo sample types routinely used in the anticancer drug discovery process.
Application Note
HTRF reveal subtle effects in tumor xenografts: a method of choice beyond Western blot
Learn about a faster, simpler, and more accurate technique for assessing protein phosphorylation and for revealing subtle drug-induced modulations compared to Western blotting.
Application Note
Sensitive detection of GPCR activation in various cellular models, based on ERK1/2 phosphorylation
This application note demonstrates how the Advanced Phospho-ERK1/2 (Thr202/ Tyr204) kit is suitable for ERK signaling pathway investigations mediated by GPCR stimulation with pharmacological compounds.
Application Note
Neuroinflammation study combining hiPSC-derived astrocytes and HTRF
Discover fully functional hiPSC-derived (disease) models and phenotypic assays for neuroinflammation drug discovery.
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