An overview of atherosclerosis

Atherosclerosis pathogenesis, cellular actors, and pathways

Atherosclerosis is a common condition in which arteries harden and become narrow due to a build-up of fatty material, usually cholesterol, and other substances such as calcium. This can lead to a range of serious health complications, including heart attack or stroke, making the disease an important contributing factor in death and morbidity in developed countries. Recent developments in our understanding of atherosclerosis from a molecular perspective include the discovery of new players in disease pathogenesis.

Included in this white paper:

• Atherosclerosis: step-by-step pathogenesis, therapeutic strategies, and recent developments
• Detailed descriptions and explanations, including a focus on pathways

For research use only. Not for use in diagnostic procedures.