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Application Note
A multiparametric live-cell cytotoxicity analysis using the Operetta High-content Analysis System
The detection of compound cytotoxicity is an essential part of drug discovery. In this work we describe a rapid and flexible image-based live cell approach to study cytotoxicity. Using a fluorophore dye mixture, multiple cellular phenotypic changes were analyzed following a toxic insult. In order to investigate different drug induced cellular responses, human hepatocytes (HepG2 cells) were treated with various compounds.
For research use only. Not for use in diagnostic procedures.
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A multiparametric live-cell cytotoxicity analysis using the Operetta High-content Analysis System