Menu
US
key-success-tips-to-perform-b-arr2-recruitment-assays_1920x400
Technical Note

Key success tips to perform β-arrestin 2 recruitment assays by using the B-arr2 recruitment kit with GPCRs

Follow this technical note to obtain better B-arr2 assay outcomes

β-arrestin 2 plays a central role in GPCR signaling pathways by regulating agonist-mediated GPCR mechanisms. The B-rr2 recruitment kit is a specific tool for monitoring cellular interaction between β-arrestin 2 and AP2 as a reading of β-arrestin 2 at the GPCR. This technical note was designed to help you optimize your B-arr2 recruitment assay results.

Discover valuable tips addressing:

  • How the fold of change measured in B-arr2 recruitment assays is related to the cell density and the expression of endogenous AP2/B-arr2 but not directly to the expression of GPCRs
  • How to carry-out the two-option protocol for B-arr2 recruitment assays and the interest of both options
  • The compatibility of the B-arr2 recruitment kit with CHO-K1 cells

For research use only. Not for use in diagnostic procedures.

To view the full content please answer a few questions

By submitting my personal data, I acknowledge that Revvity Inc. and its affiliates (“Company”) will process my personal data provided above consistent with the Company’s Privacy Policy available here.

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Download Resource

Key success tips to perform β-arrestin 2 recruitment assays by using the B-arr2 recruitment kit with GPCRs

Download Technical Note