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Technical Note

The Inositol-Phosphate approach, a robust and stable platform for HTS of Gq coupled GPCR

Overcome calcium assay signal’s transient nature in Gq coupled GPCR studies

This Technical Note shows data confirming the relevance of using IP-One assays for the high throughput screening of Gαq-coupled GPCRs. Ease of use, signal stability, consistency and robustness - the note thoroughly reviews all of these and features.

Principle and protocol of IP-One assays
Guidelines to data processing
Detailed examples and result analysis

For research use only. Not for use in diagnostic procedures.

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The Inositol-Phosphate approach, a robust and stable platform for HTS of Gq coupled GPCR

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