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Application Note
Induced regulatory T cell suppression assay for compound screening
To investigate immunomodulators on iTreg function, compound screening can be a valuable tool to help decipher the immunological profile of drug target candidates.
In this application note, we present our rapid high-throughput in vitro functional assay to assess the effect of compounds on iTreg function to enhance or inhibit their suppressive activity on T cells.
This assay can be run complementary to our previously developed iTreg polarization assay to elucidate the overall activity of compounds on iTreg biology.
For research use only. Not for use in diagnostic procedures.
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Induced regulatory T cell suppression assay for compound screening