Menu
US
improve-protac-targeting-kinase_1920x400
Application Note

Improve PROTAC Targeting Kinase Discovery with HTRF Binding Kits

HTRF assays to assess PROTAC® compounds

Kinases constitute about 2% of all human genes and are essential proteins involved in signal transduction. They regulate numerous biological events, such as cell growth and proliferation. Kinase dysfunctions are associated with numerous diseases and current treatments have many side effects. Targeted degradation could be an option to overcome these, and PROteolysis Targeting Chimera (PROTAC®) is one of the latest trending tools. This is why we have prepared a note compiling experiments carried out to characterize PROTAC® compounds using HTRF™ technology.

Featured in this note:

  • Assay principle and workflow
  • Freshly published graphs and data
  • Informative materials and methods, including references

For research use only. Not for use in diagnostic procedures.

To view the full content please answer a few questions

By submitting my personal data, I acknowledge that Revvity Inc. and its affiliates (“Company”) will process my personal data provided above consistent with the Company’s Privacy Policy available here.

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Download Resource

Improve PROTAC Targeting Kinase Discovery with HTRF Binding Kits

Download Application Note