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Application Note

Fc-Receptor binding ADCC assays utilizing AlphaLISA technology: Characterization of hIgGs and FcγRIIIa

Fc Receptors (FcRs) are cell-surface proteins found on various cell types and play a role in the adaptive immune system. The Fc-Gamma Receptors (FcγRIIIa) are part of the immunoglobulin superfamily and are crucial for the function of therapeutic antibodies.

This application note demonstrates how AlphaLISA assay can be used to determine the binding activity of human IgG Fc fragment to human FcγRIIIa and to study how other antibodies bind to FcγRIIIa.

For research use only. Not for use in diagnostic procedures.

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Fc-Receptor binding ADCC assays utilizing AlphaLISA technology: Characterization of hIgGs and FcγRIIIa

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