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Application Note

Download your application note on nuclear receptor ligand identification with HTRF

Dive deeper into NASH investigation

Nuclear Receptors (NRs) regulate gene transcription by DNA binding. Interaction of NRs with an agonist triggers conformational changes and enables the recruitment of coactivators (CoA), leading to gene transcription. The activity of several NRs has been associated to NAFLD, bringing about the emergence of new therapeutic targets in NASH.

Now, thanks to HTRF technology, you can monitor NR/CoA recruitment easily. With this application note you will:

  • Benefit from HTRF technology in your research to identify potent NR ligands
  • Discover the potential of HTRF PPi reagents to revolutionize your research
  • Build robust and convenient NR/CoA recruitment assays for your research

For research use only. Not for use in diagnostic procedures.

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Download your application note on nuclear receptor ligand identification with HTRF

Download Application Note