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Case Study

B cell selection and therapeutic antibody characterization using the Operetta high content imaging system

This case study illustrates how Revvity’s high-content imaging solutions support the therapeutic antibody development. Two steps in the workflow - the clonal B cell selection and the functional antibody characterization - rely on high-content screening using the Operetta system.

The coupling of the Operetta system to a plate::handler workstation allows the running of plates both day and night, further increasing the throughput. In addition, the EnVision multimode plate reader and the JANUS™ Automated Workstation are essential parts of the workflow that contribute to the throughput of the process and can reduce the variability of liquid handling steps.

For research use only. Not for use in diagnostic procedures.

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B cell selection and therapeutic antibody characterization using the Operetta high content imaging system