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Application Note
Accelerate Parkinson's disease drug discovery with no-wash LRRK2 assays
Unlock the potential of HTRF™ LRRK2 immunoassays to support and advance Parkinson's disease drug discovery. This comprehensive application note provides valuable insights for rapid detection and characterization of LRRK2 targeting agents.
This application note features:
- In-depth understanding of the role of LRRK2 in Parkinson's disease and its pathogenic mutations.
- Detailed assay principles and formats for accurate measurement of phosphorylated LRRK2 and total protein levels.
- Robust validation data showcasing the effectiveness of various LRRK2 kinase inhibitors and PROTAC degraders.
- Practical recommendations for optimizing assay conditions and ensuring reliable results.
For research use only. Not for use in diagnostic procedures.
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Accelerate Parkinson's disease drug discovery with no-wash LRRK2 assays