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Culture
When it comes to developing advanced physiological models — it’s critical to select the cell model with the right genomic context and biological function to recapitulate a healthy or diseased phenotype.
Achieving this level of accuracy requires tightly controlled culture conditions and reliable cell counting for cell seeding. Choosing a 2D or 3D cell culture method depends on the biological question, complexity of the desired model, and readout technology. Cells can be grown as monolayers, single spheroids in ultra-low attachment (ULA) plates, or cultured in hydrogels, offering a variety of options to enhance your research capabilities. Count on us to expertly scale up these methods, utilizing liquid handling techniques.
Featured products:
GrowDex Hydrogels
Microplates
Fontus Workstations
Cell Counting & Image Cytometry Instruments
Viral Vector Products
Recombinant Proteins
CRISPR Technologies
Treatment
In modern drug discovery, multiple screening methods play a vital role in identifying potential drug targets and eventual drug candidates. Traditionally, small molecule libraries were screened for compounds acting on a known molecule or for a desired biological effect. However, a drug candidate is only as good as its target.
To ensure the utmost precision, today’s drug discovery leverages gene editing or gene silencing methods such as CRISPR or siRNAs to identify suitable drug targets. Understanding the causal gene behind a phenotype or genes that contribute to a phenotype can significantly boost the confidence in a new drug candidate. Get ready to experience advancements in your research as we deliver convenience and efficiency.
Featured products:
Fontus Workstations
CRISPR Technologies
RNA Interference
Model Analysis
Selecting the right method for measuring the biological response of 3D cell models depends on the specific research question and the characteristics of the model system in use.
Whether you’re repeatedly monitoring microtissue size or measuring sensitive detection of secreted proteins, each readout type poses unique challenges that can be overcome with the right tools. Our microplate readers, high-content analysis systems, and innovative reagents are complemented by specially designed microplates. Together, they shine a light on your samples, offering powerful insights to propel your research forward.
Featured products:
LabChip GX Touch Nucleic Acid Analyzer
3D Cell Model Imaging and Analysis
Microplate Readers
Immunoassays
Since their introduction in the 1950’s, immunoassays have been an integral part of research and drug discovery.
Luminescence Assays
Nucleic Acid Isolation
Cell Counting & Image Cytometry Instruments
Multiomics and TotalSeq Reagents by BioLegend
Data Analysis
Extracting insights from complex 3D datasets is no easy task. It requires the meticulous analysis of readouts and vast amounts of information (in context). But no worries—we’ve got you covered.
With our scientific software and informatics solutions, you gain the ultimate tools to optimize 3D cell model imaging. Seamlessly aggregate, search, mine, and visualize critical data, converting it into actionable insights that drive your research forward. We are here to help you meet the challenges of data analysis head on—so you can embark on a journey of ground-breaking discoveries.
Featured products:
Signals Image Artist
Signals Image Artist has powerful capabilities for processing, analyzing, storing, and sharing all your high-content screening and cell imaging data – so you can significantly cut your time to results.
Signals Research Suite
Make your innovations a reality with the first unified, cloud-native SaaS R&D platform that streamlines scientific complexity and promotes collaboration.
Services
Discover how our complex cell model screening services can accelerate your drug discovery and development goals. Our team leverage Revvity’s advanced imaging technologies and an extensive library of spheroids and primary immune cells to provide more biologically relevant data. This allows for better prediction of human responses to therapeutic interventions in immuno-oncology.
From assay design to high-throughput screening, we provide an end-to-end service that supports every phase of your drug development, with dedicated project management you can trust.
Featured services:
Advanced 3D cell culture models services
Our complex cell model screening services leverage Revvity’s advanced imaging technologies and an extensive library of spheroids and primary immune cells, providing more biologically relevant data.