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IVISense Fluorescent Labels & Dyes

Developing novel fluorescent probes to visualize and quantify biomolecular processes and pathways within the context of a living animal requires using fluorescent dyes optimized for in vivo imaging. We offer a range of IVISense™ fluorescent dyes and cell labeling dyes for imaging cells, proteins, antibodies, and molecules for your research.

Protein/chemical labeling fluorescent dyes:

Tested and selected in vivo to ensure minimal non-specific uptake in tumors, our fluorescent dyes are available in multiple wavelengths, making them ideal for multiplexing.

Cell labeling dyes:

Label a variety of cells brightly and uniformly with options to avoid harsh organics known to affect cell function.

With high solubility and reactivity, excellent stability, and in vivo optimization, our labels and dyes offer superior brightness and are validated for in vivo and in vitro imaging.

For research use only. Not for use in diagnostic procedures.

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  • Label peptides, small molecules, proteins, antibodies, macromolecules, and nanoparticles with IVISense fluorescent dyes and self quenching dyes.
  • Track mammalian cells including stem cells, T-cells, macrophages and more with IVISense 680 or IVISense DiR fluorescent cell labeling dyes.
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IVISense™ fluorescent imaging probes

Revvity’s IVISense™ 750 fluorescent dyes for labeling proteins, antibodies, peptides, and small molecules offer excellent brightness optimized for in vivo and in vitro imaging applications. IVISense 750 fluorescent dyes are available in self-quenching format as NHS esters or self-quenching maleimide reactive dyes for conjugation to either free amine (-NH3) or free thiol (-SH) containing molecules.

List price:
USD 173.94 - 653.65
IVISense™ fluorescent imaging probes

Revvity’s IVISense™ 680 fluorescent dyes for labeling proteins, antibodies, peptides, and small molecules offer excellent brightness optimized for in vivo and in vitro imaging applications. Our IVISense 680 fluorescent dyes are available in the following formats: Labeling kit containing necessary reagents for carrying out labeling reaction and purifying labeled product NHS esters for conjugation to free amine (-NH3) containing molecules MAL (Maleimide) reactive dyes well suited for labeling thiol and cysteine containing molecules NHS self-quenching dyes for generating your own fluorogenic in vivo imaging probes

List price:
USD 169.34 - 663.51
IVISense™ fluorescent imaging probes

Revvity’s IVISense™ 800 fluorescent dyes for labeling proteins, antibodies, peptides, and small molecules offer excellent brightness optimized for in vivo and in vitro imaging applications. IVISense 800 fluorescent dyes are available as NHS esters for conjugation to free amine (-NH3) containing molecules.

Part Number: NEV11107, NEV11108
List price:
USD 171.46 - 659.06
IVISense™ fluorescent imaging probes

IVISense™ 645 fluorescent dyes can be used for a variety of preclinical in vivo imaging and in vitro applications. Ideal for labeling proteins, antibodies, peptides and small molecules, IVISense 645 fluorescent dyes are highly hydrophilic and suitable for single or multiple dye loading. Our IVISense 645 fluorescent dyes are available as NHS esters or maleimide (MAL) reactive dye forms for conjugation to either free amine (-NH3) or free thiol (-SH) containing molecules.

List price:
USD 156.34 - 660.13
IVISense™ DiR 750 Fluorescent Cell Labeling Dye (XenoLight)

IVISense™ DiR 750 (XenoLight™ DiR) NIR fluorescent dye can be used for non-invasive imaging of T-cell or stem cell homing in vivo.

Part Number: 125964
List price:
USD 241.76
IVISense™ 680 fluorescent cell labeling dye

Label and track mammalian cells including stem cells, T-cells, macrophages and more with IVISense™ 680 fluorescent cell labeling dye (VivoTrack™). IVISense 680 is an NIR fluorescent lipophilic labeling dye that intercalates in the cell membrane. With high solubility and excellent stability, Revvity’s IVISense 680 fluorescent cell labeling dye offers high brightness and uniform labeling, ideal for cell detection in vitro and longitudinal cell tracking in vivo across many applications including inflammation, immunology, and stem cell research.

Part Number: NEV12001, NEV12000
List price:
USD 110.77 - 369.56
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Best practices for designing an effective in vivo fluorescence imaging study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into disease processes and treatment effects. Designing an effective study from the beginning can help save time and resources. Learn about several important best practices, from proper probe selection to study design to imaging technique tips and tricks needed to generate meaningful biological information from your in vivo fluorescence imaging studies.

Application Note
Application Note
Cell labeling and tracking in vivo using IVISense NIR fluorescent dyes

Fluorescent dyes have been used for many years to label cells for microscopy studies, and a variety of dyes in the visible fluorescence spectrum are available to label different cellular compartments and organelles. Efficient delivery of the fluorophore to the cell without excessively modifying surface proteins or perturbing cell function is the major biotechnological challenge. Our IVISense® NIR fluorescent cell labeling dyes with high solubility, reactivity, and excellent stability, offers superior brightness ideal for detection and longitudinal cell tracking in vivo across many applications including inflammation, immunology, and stem cell research. This application note highlights the benefits of using IVISense cell labeling fluorescent dyes in your in vivo imaging studies. Track stem cells, T cells, macrophages and many other cell types longitudinally in vivo Water soluble - no need for harsh organics such as DMSO or ethanol, chemicals known to affect cell function. Homogeneous cell staining with no impact on cell viability Optimized for in vivo use with Revvity’s IVIS® optical imaging platform

eBook
eBook
In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And our hard-earned expertise makes us a trusted provider of pre-clinical imaging solutions— with more than 20,000 peer reviewed articles as proof.

Guide
Guide
IVISense fluorescent probe selector guide for oncology research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and biological functioning to better understand and characterize disease processes and treatment effects earlier within the context of a biological system. This selector guide for IVISense ™ fluorescent probes is a powerful tool to help advance your oncology research. By matching probe properties to specific biology and biomarker characteristics, you can better understand how imaging and quantification of early biological changes associated with disease development, therapeutic efficacy, and drug-induced tissue changes can be realized.

Protocol/SOP
Protocol/SOP
PROTOCOL: Antibody and protein near infrared (NIR) labeling with IVISense 645 NHS fluorescent dye

Protocol/SOP
Protocol/SOP
PROTOCOL: Antibody and protein near infrared (NIR) labeling with IVISense 680 NHS fluorescent dyes

Protocol/SOP
Protocol/SOP
PROTOCOL: Antibody and protein near infrared (NIR) labeling with IVISense 800 NHS fluorescent dye

Protocol/SOP
Protocol/SOP
PROTOCOL: Antibody and protein near infrared (NIR) labeling with IVISense MAL fluorescent dyes

Protocol/SOP
Protocol/SOP
PROTOCOL: Antibody and protein NIR labeling with IVISense NHS self-quenching dyes