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Scientific Poster
Achieving CAR-T cell generation in a single intervention using a multiplex base editing system
In this poster, we highlight an example configuration of the Pin-point technology for the streamlined generation of allogeneic CAR-T cells and hypoimmunogenic iPSCs.
Application Note
Increasing the targeting scope and precision of next-generation gene editing technology
In this application note, we demonstrate the Pin-point™ base editing system as a novel nucleaseagnostic modular platform for increasing the targeting scope and precision of next-generation gene editing technology.
Brochure
The Pin-point™ platform: A novel modular base editing system
This presentation provides an overview of the Pin-point base editing platform by describing its key benefits, how it works, and supporting data.
Whitepaper
Optimizing AAV manufacturing: a scalable harvest protocol
As demand for recombinant AAV (rAAV) vectors continues to rise, scalable and efficient manufacturing processes are essential for advancing gene therapy.
Flyer
CD34+ hematopoietic stem cells: Research with confidence
This flyer introduces CD34+ hematopoietic stem cells outlining features and benefits
Whitepaper
ImmuSignature™ MLR: Rapid high-throughput assessment of therapeutic immunogenicity
This white paper describes how a rapid immunogenicity assessment screening can provide invaluable support for IND applications.
Literature - Publication Review
The future of immunotherapy gets brighter with base editing
This literature review discusses how base editing technology addresses the shortcomings of other gene editing technologies for immunotherapy.
Whitepaper
Assessing the epigenetics of T cell exhaustion using CRISPR screens
Explore the epigenetics of T cell exhaustion and practical techniques to assess immune cell epigenetic regulators using CRISPR screens.
Whitepaper
Base editing and stem-cell based therapies
This white paper explores how base editing is advancing iPSCs in the fields of basic science, regenerative medicine and immunotherapy.
Whitepaper
Addressing the challenges in solid tumor therapy with base editing
Read this white paper to learn about how base editing is helping to address key challenges in immunotherapies for solid tumors.
Scientific Poster
A single-step process for engineering hypoimmunogenic pluripotent stem cells with the Pin-point™ platform
Learn about the utility of the Pin-point™ base editing platform for the engineering of allogeneic PSCs.
Webinar
wbs-strategies-for-therapeutic-screening-in-immune-cells
This on-demand webinar provides an overview into how integrating immune cell screening into drug discovery pipelines can provide insight into the immunogenicity of individuals and help to quickly characterize them.
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