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  • Who we serve
    • Academia
      Explore BioLegend

      Learn about our world class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.

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    • Pharma / Biotech
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    • Clinical Laboratories
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    • Healthcare Professionals
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    • Contract Research Organizations
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  • Products
    • Research & Development
      • Genomic Analysis
        • IncRNA in Functional Studies
        • Nucleic Acid Isolation
        • NGS Workflows
        • Microplate Readers
        • Microfluidic Nucleic Acid Analysis
        • CRISPR Technologies
        • RNA Interference
        • Transfection and Ancillary Reagents
        • Oligonucleotide Custom Synthesis
        • cDNAs and ORF Clones
        • Single-Cell Sequencing
        • Labeled Nucleotides
        • qPCR
        • Library Prep Kits
        • Magnetic Beads
        • Viral Vector Products
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      • Protein Analysis
        • Binding Assays
        • Immunoassays
        • Microfluidic Protein Characterization
        • Microplate Readers
        • Microplates
        • Recombinant Proteins
        • Western Blotting
        • Sample Dissociation
        • M-PVA Magnetic Beads
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      • Cell Analysis
        • Cell Isolation
        • Cell Lines & Stem Cells
        • Cell Counting and Image Cytometry
        • Cell Health & Viability
        • Cellular Imaging & Analysis
        • Immunoassays
        • In Vivo Imaging
        • Microplates
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      • Research Solutions
        • Immunoassays Solutions
        • pHSense Reagents
        • Biomarker Discovery
        • Cell and Gene Therapy
        • GMP Workflows
        • Biologics
        • Small Molecule Drug Discovery
        • Disease Research
        • Target Class
        • Drug Development
        • Precision Medicine Research
        • Functional Genomic Screening Solutions
        • Assay Development Workflows
        • Physiological Model Solutions
        • Biobanking Workflows
        • Agrigenomics Workflows
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    • Clinical & Diagnostics
      • Reproductive Health
        • Maternal and Prenatal Testing
        • Newborn Screening
        • Newborn Sequencing Research
        • Pregnancy-Relevant Infections
        • Endocrine Reproductive
        • Cell-free DNA Analysis
        • Neonatal Research
        • Preimplantation Genetic Testing
        • PlGF Testing Research
        • Molecular Cytogenetics
        New IVD Mimix™ reference standards for oncology workflows.

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      • Infectious Diseases
        • Tuberculosis Management
        • EUROIMMUN Solutions
        • IDS Solutions
        • Nucleic Acid Isolation for Pathogen Detection
        • Cytomegalovirus
        • SARS-COV-2 Testing Solutions
        • Bacterial & Viral Nucleic Acid Isolation
        • Metagenomics
        New IVD Mimix™ reference standards for oncology workflows.

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      • Cancer
        • ASR Flow Cytometry Antibodies
        • HPV Testing
        • ctDNA Workflows
        • miRNA-seq Analysis
        • Exosome/cfRNA Analysis
        • Targeted Sequencing
        • Mimix Reference Standards
        • Functional Testing
        NEW! Mimix IVD reference standards

        Providing diagnostic labs with trusted quality controls for developing tests and monitoring workflows, with the added assurance of IVD marking. Explore our newest MimixTM controls.

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      • Autoimmunity
        • EUROIMMUN Solutions
        • IDS Solutions
        New IVD Mimix™ reference standards for oncology workflows.

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      • Endocrinology
        New IVD Mimix™ reference standards for oncology workflows.

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      • Allergy
        New IVD Mimix™ reference standards for oncology workflows.

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      • Neurodegeneration
        • Alzheimer's Disease
        • Amytrophic Lateral Sclerosis (ALS)
        • Neurogranin
        • BACE1
        New IVD Mimix™ reference standards for oncology workflows.

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      • Rapid Patient Testing
        New IVD Mimix™ reference standards for oncology workflows.

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      New IVD Mimix™ reference standards for oncology workflows.

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    • Reagents
      • BioLegend
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      • Cellular Imaging Reagents
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      • chemagic Nucleic Acid Purification Kits
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      • CRISPR Technologies
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      • GPCR Research Reagents
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      • Immunoassays
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      • In Vivo Imaging Reagents
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      • Liquid Scintillation Cocktails
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      • NGS Library Prep Kits
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      • pHSense Reagents
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      • qPCR
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      • Radiochemicals
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      • RNA Interference
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      • Primary and Secondary Antibodies
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    • Platforms & Automation
      • Nucleic Acid Purification
        • chemagic Applications
        • chemagic IVD Instruments
        • chemagic IVD Kits
        • chemagic Instruments
        • chemagic Kits
        • M-PVA Magnetic Beads
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Automated Liquid Handling
        • Liquid Handling Workstations
        • Automated Liquid Handling Applications
        • Liquid Handling Consumables & Accessories
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Integrated Lab Automation
        • Automated Plate Loading
        • Workstation Modules
        • Scheduling & Control Software
        • Robotics
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Microfluidic Analysis
        • Microfluidic Protein Characterization
        • Microfluidic Nucleic Acid Analysis
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Detection Solutions
        • Plate Reader Accessories
        • Microplate Readers
        • Radiometric Detectors
        • Radiochemicals
        • Liquid Scintillation Cocktails
        • Radiometric Consumables & Accessories
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Imaging
        • Cellular Imaging & Analysis
        • In Vivo Imaging
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Cell Counting and Image Cytometry
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Sample Homogenization
        • Homogenizers
        • Homogenizer Accessories
        • Homogenizer Consumables
        • Sample Centrifugation
        • Sample Sonication
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • In Vitro Diagnostics (IVD) Platforms & Automation
        • IVD Nucleic Acid Isolation
        • IVD Automated Liquid Handling
        • IVD Radiometric Detectors
        • EUROIMMUN Instruments
        • IDS Instruments
        • Clinical Applications
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Consumables & Accessories
        • Cassettes
        • Cell Harvesters
        • In Vivo Imaging Accessories
        • High-Content Imaging Accessories
        • Microplates
        • Radioactive Spill Cleaners
        • Scintillation Cocktails
        • Transfer Membranes
        • Charcoal Traps
        • Homogenizer Accessories
        • Homogenizer Consumables
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Instrument Service & Maintenance
        • On Demand Equipment Service
        • Equipment Service Plans
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      New! Cellometer™ Ascend™

      Explore our cell counting and image cytometry solutions.

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    • Consumables & Accessories
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    • Signals Software
      • All Products
        • Signals One
        • ChemDraw
        • Spotfire®
        • Signals Clinical
        • Signals Notebook
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      • All Solutions
        • Biology
        • Discovery Chemistry
        • Clinical & Translational
        • Specialty Chemicals
        • Food/Flavor/Fragrance
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    • Revvity Omics Services
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  • Services
    • Preclinical Services
      • Antibody Drug Conjugate Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Complex Cell Model Screening Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Base Editing Platform
        • Pin-point base editing platform cell line engineering services
        • Pin-point base editing platform pooled tiled screening services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Immune Cell Screening
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Functional Genomic Screening Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Cell Panel Screening
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Cell Line Engineering
        • CHOSOURCE CLE Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Viral Vector Engineering and Manufacture
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      Preclinical services

      Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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    • Revvity Omics Services
      • Revvity Omics Clinical Services
        • Cytogenomics
        • Global Laboratory Network
        • Metabolic Testing
        • Newborn Screening Services
        • Prenatal Screening Services
        • Proactive Testing
        • Rare Disease Testing
        • Specialized and Customized Assays
        • Sponsored Testing Programs
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Revvity Omics Pharma Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Clinical & Testing Services
      • Revvity Omics Clinical Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

        Learn more

      • Revvity Omics Pharma Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Cellular and Humoral Immunoassays
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Tuberculosis Testing Services
        • Oxford Diagnostic Laboratories Service Closures
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Customization Services
      • Assays and Reagents
        • Assay Development
        • Compound profiling
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Microplate Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Custom Conjugation & Labeling
        • Custom Labeling
        • Small Molecule
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Radiosynthesis and Labeling
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Licensing
      • Gene Delivery Licensing
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Gene Expression Systems
        • CHOSOURCE Platform
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Pin-point™ Base Editing Platform
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Virus Screening
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      CHOSOURCE expression platform

      Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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    • Viral Vector Engineering and Manufacture
      • AAV Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Lentivirus Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

        Learn more

      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Instrument Service & Maintenance
      • AV Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Equipment Service Plans
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

        Learn more

      • On-demand Equipment Service
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

        Learn more

      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

      Learn more

    • Customer Training
      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • OEM Solutions
      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    T-SPOT.TB testing services.

    Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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  • Company
    • Purpose
      • Approach
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      • Our Story
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      • Leadership
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    • Careers
      • Careers Home
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      • Why Revvity
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      • Search Jobs
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    • Investor Relations
      • Events
        Investor Day 2024

        Driving meaningful innovation that profoundly impacts science and human lives.

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      • Financials
        Investor Day 2024

        Driving meaningful innovation that profoundly impacts science and human lives.

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      • Stock Info
        Investor Day 2024

        Driving meaningful innovation that profoundly impacts science and human lives.

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      Investor Day 2024

      Driving meaningful innovation that profoundly impacts science and human lives.

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    • ESG
      • Environmental
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      • Social
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      • Governance
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    • News
      • Announcements
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      • Awards
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      • Media Alerts
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      • Press Coverage
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  • Resources
    • Product Support
      • Application Support Knowledge base (ASK)
        Tech documents, at your fingertips.

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      • SpectraViewer
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      • RAD Calculator
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    • Blog
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    • Events
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    • Customer Training
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    • Help Center
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      • Cell Line Terms & Conditions
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    • Knowledge Base
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      • Sample homogenization applications and protocols
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      • Newborn screening disorders
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      • TB testing services
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      • Investigator led studies
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      • Tuberculosis (TB)
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  • Brands
      Revvity Brands
    • BioLegend

    • EUROIMMUN

    • Revvity Omics

    • Revvity Signals

    • Tulip Diagnostics

    • ViaCord

    • Popular Revvity Product Brands
    • AlphaLISA and SureFire Ultra

    • BioQule NGS

    • chemagic

    • EnVision Nexus

    • Fontus

    • HTRF

    • IVIS

    • LEGENDplex

    • Opera Phenix

    • T-SPOT

    • TotalSeq

    • View all Revvity brands
  • Welcome to Revvity: renowned brands and boundless innovation.

    Hearing the word "can't" is our call to action!

    We help scientists, researchers, and clinicians overcome the world's greatest health obstacles.

    View our story

    Featured brand: BioLegend

    Learn about our world-class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.

    Visit BioLegend.com

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  • IVISense Vascular 680 Fluorescent Probe (AngioSense)

IVISense Vascular 680 Fluorescent Probe (AngioSense)

SDSTDSKnowledge base
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak View All
IVISense Vascular 680 Fluorescent Probe (AngioSense)
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes

In vivo optical imaging of vascular changes and vascular leak is an emerging modality for studying altered physiology in a variety of different cancers and inflammatory states. In oncology, increases in tumor vascular permeability can be an early indicator of tumor angiogenesis. In inflammatory disease increased vascular permeability can indicate alterations in fluid homeostasis in an acute edema response or in chronic organ conditions.

Revvity’s IVISense™ Vascular NIR fluorescent probes (AngioSense®) are designed to evaluate vascular changes to better understand various disease states or provide valuable information on the effects of drug candidates earlier in the development process.

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Feature Specification
Unit Size 1 vial (10 doses)
Specificity Passive; non-specific systemic circulation
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In vivo optical imaging of vascular changes and vascular leak is an emerging modality for studying altered physiology in a variety of different cancers and inflammatory states. In oncology, increases in tumor vascular permeability can be an early indicator of tumor angiogenesis. In inflammatory disease increased vascular permeability can indicate alterations in fluid homeostasis in an acute edema response or in chronic organ conditions.

Revvity’s IVISense™ Vascular NIR fluorescent probes (AngioSense®) are designed to evaluate vascular changes to better understand various disease states or provide valuable information on the effects of drug candidates earlier in the development process.

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Product variants
Wave Length: 680 nm
Part #:
NEV10054EX
List price
USD 580.45
Your online price:
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Wave Length: 750 nm
Part #:
NEV10011EX
List price
USD 572.98
Your online price:
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For research use only. Not for use in diagnostic procedures.
Total list price:
USD 580.45
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IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense Vascular 680 Fluorescent Probe (AngioSense)
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense Vascular 680 Fluorescent Probe (AngioSense)
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
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  • SDS, COAs, manuals and more
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Product information

  • Overview
  • Specifications
  • Image gallery

Overview

IVISense Vascular 680 fluorescent imaging probe (AngioSense 680EX) is an in vivo blood pool vascular agent that remains localized in the vasculature for extended periods of time (0-4 hrs) enabling imaging of vascularity, perfusion, and vascular permeability at a wavelength of 680 nm. The probe accumulates in tumors and arthritic joints at 24 hrs. IVISense Vascular 680 fluorescent agent can be used as a single probe or multiplexed with probes at other wavelengths.

Specifications

Brand
IVISense
Fluorescent Agent Type
Vascular
Imaging Modality
Fluorescence
Shipping Conditions
Shipped in Blue Ice
Specificity
Passive; non-specific systemic circulation
Storage Conditions
+2 to +8 °C
Therapeutic Area
Angiogenesis
Arthritis
Inflammation
Oncology
Vascular
Unit Size
1 vial (10 doses)
Wave Length
680 nm

Image gallery

IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense Vascular 680 Fluorescent Probe (AngioSense)
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense Vascular 680 Fluorescent Probe (AngioSense)
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
Breast tumor in mouse using AngioSense fluorescent probe and IVIS SpectrumCT system
Vascular leak
IVISense™ fluorescent imaging probes

Resources

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  • Protocol/SOP (1)
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1-1 of 1 Resources
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eBook
In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...

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SDS, COAs, manuals and more

Are you looking for technical documents related to the product? We have categorized them in dedicated sections below. Explore now or request your COA/TDS, SDS, or IFU/manual.

Safety data sheet
  • Language
    English
    Country
    United States
    Name
    SDS IconSDS_NEV10054EX_US_EN.pdf
  • Language
    English
    Country
    EU
    Name
    SDS IconSDS_NEV10054EX_EU_EN.pdf

Unable to find the relevant SDS? Try Searching or Request an SDS

Technical data sheet
  • Lot Number
    ANY
    Lot Date
    September 6, 2023
    Name
    SDS IconNEV10054EX.pdf

Unable to find the relevant TDS? Try Searching or Request a TDS

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