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LabChip AAV Empty/Full Chip bundle

The LabChip® AAV Empty/Full chip bundle provides two microfluidic platforms for rapid AAV protein characterization and AAV DNA measurement for the characterization of Empty/Full ratio of AAV particles using the LabChip GXII Touch System.

These reagents are fully validated and compatible with AAV1, AAV2, AAV6, AAV8 and AAV9

For research use only. Not for use in diagnostic procedures.

Product Variant
Sample Type: DNA, Protein
Part #:
CLS158860
List Price
USD 6,360.55
Feature Specification
Application DNA Analysis
Protein Analysis
Unit Size 2 chips
Feature Specification
Application DNA Analysis
Protein Analysis
Unit Size 2 chips

Overview

Fast, Automated Analysis of AAV Viral Proteins and DNA analysis:

The AAV Empty/Full protein and DNA chip allow the measurement of Adeno-associated virus (AAV) vector samples with minimal sample volume as low as 5 µL each and provides a fast and reproducible method to:

  • Measure viral protein stoichiometry.
  • Capsid purity
  • AAV DNA genomic integrity
  • AAV DNA purity

All these traces are obtained with electrophoresis run time of <2 minute per sample. Each chip can be used to analyze up to 250 samples and can be used with the LabChip GXII Touch HT Characterization System.

Note: The HT chips are not compatible with GX Touch/GXII Touch 24 instruments. The LabChip Software version 1.13 and LabChip Reviewer Software version 5.11 or higher are needed for AAV Empty/Full Analysis

Protein Detection for Empty/Full Analysis:

The LabChip AAV Pico Protein Analysis Assay automates AAV Empty/Full determination when used in combination with the LabChip AAV DNA Analysis Assay. The software includes data analysis for AAV Empty/Full determination using referencing measurements to an AAV standard (sold separately). AAV Empty/Full calculation can be obtained on AAV samples of concentration 1E12 VP/mL in phosphate saline formulation buffers. For this, the following items can also be combined:

  • AAV Emtpy/Full chip bundle (CLS158860)
  • AAV Empty/Full Reagents bundle (CLS158863)
  • AAV Standard (CLS157467)

Specifications

Application
DNA Analysis
Protein Analysis
Automation Compatible
Yes
Instrument Compatibility
LabChip GXII Touch
Sample Type
DNA
Protein
Shipping Conditions
Shipped in Blue Ice Soft
Technology
Microfluidic Electrophoresis
Unit Size
2 chips

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Resources

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Product Note Icon
Product Note
Automated characterization of proteins and nucleic acids

Read the LabChip® GXII Touch protein characterization system product note to learn about an automated alternative to traditional...

Application Note Icon
Application Note
Automated microfluidic capillary electrophoresis for measurement of full and empty adeno‑associated virus capsids.

In this application note we describe a microfluidic capillary electrophoresis method that uses the LabChip® GXII Touch™ Protein...

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